If you've started reading about weight-loss injections, the names blur together fast: Ozempic, Wegovy, Mounjaro, Saxenda. They're related, they're not identical, and the choice between them is a medical decision for your doctor — not something to settle from a blog. What a dietitian can do is explain the landscape clearly and tell you the part that matters most for your results.
The short version
Ozempic and Wegovy are both semaglutide — the same active ingredient. Ozempic is licensed for type-2 diabetes and Wegovy for weight management, but they work the same way: they mimic a gut hormone called GLP-1 that slows digestion and reduces appetite. Mounjaro is tirzepatide, which acts on two hormone pathways (GIP as well as GLP-1) and in trials has tended to produce larger appetite and weight effects for many people. Saxenda (liraglutide) is an older, shorter-acting option in the same family.
Why the differences matter less than you'd think
Which medication you end up on depends on your health history, what your prescriber recommends, availability and cost. But here's the thing they all share: every single one curbs how much you eat without telling you what to eat. That gap is identical across all of them — and it's where muscle loss, nutrient shortfalls, nausea and post-medication rebound come from.
The half that's the same on every jab
Whatever the prescription, the nutrition job doesn't change: protect your muscle with enough protein, keep your fibre and micronutrients up while you're eating less, manage side-effects with food, and build the habits that hold your result when you eventually stop. That's the half I own — and it works the same whether you're on Ozempic, Wegovy or Mounjaro. Always take medical and dosing decisions with your doctor; bring me the eating side.
